Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pleiotropy01:33

Pleiotropy

41.4K
Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
41.4K
Unusual Results01:16

Unusual Results

3.4K
Unusual results are those that have a very low chance of occurring. Unusual results can be identified using probabilities and the range rule of thumb. In problems involving probability, unusual results can be observed in 2 instances – an unusually high number of successes or an unusually low number of successes.
According to the range rule of thumb, any value above or below two standard deviations, 2σ  from the mean, μ  is considered unusual.
Maximum unusual value =...
3.4K
Wilcoxon Rank-Sum Test01:21

Wilcoxon Rank-Sum Test

377
The Wilcoxon rank-sum test, also known as the Mann-Whitney U test, is a nonparametric test used to determine if there is a significant difference between the distributions of two independent samples. This test is designed specifically for two independent populations and has the following key requirements:
377
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

35.5K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
35.5K
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

43
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
43
Karyotyping01:17

Karyotyping

63.3K
Overview
63.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Viral genetics and transmission dynamics in the second wave of mpox outbreak in Portugal and forecasting public health scenarios.

Emerging microbes & infections·2024
Same author

Allergic contact dermatitis to sodium metabisulphite in a rotigotine transdermal therapeutic system.

Contact dermatitis·2024
Same author

Bone-Patellar Tendon-Bone Augmentation With Gracilis Tendon: The Bone-Patellar Tendon-Bone Plus Technique.

Arthroscopy techniques·2024
Same author

Dupilumab in Patients with Atopic Dermatitis: A Multicentric, Long-Term, Real-World Portuguese Study.

Dermatology and therapy·2024
Same author

Clinical course and disease burden of patients with generalized pustular psoriasis in Portugal: a multicenter retrospective cohort study.

The Journal of dermatological treatment·2024
Same author

Small Bowel Obstruction Secondary to a Spontaneous Intramural Jejunal Hematoma.

Acta medica portuguesa·2024

Related Experiment Video

Updated: Oct 6, 2025

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome
05:12

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome

Published on: September 19, 2019

6.7K

Wilkie's Syndrome: An Unexpected Finding.

Mariana Claro1, Diogo Sousa1, Alberto Abreu da Silva1

  • 1General Surgery, Unidade Local de Saúde do Litoral Alentejano, Santiago do Cacém, PRT.

Cureus
|January 20, 2022
PubMed
Summary

Wilkie's syndrome, a rare duodenal obstruction caused by superior mesenteric artery (SMA) compression, presents with non-specific symptoms. Laparoscopic duodenojejunostomy offers effective treatment for severe cases.

Keywords:
duodenojejunostomyintestinal obstructionpost-prandial abdominal painsuperior mesenteric artery syndromewilkie's syndrome

More Related Videos

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
07:15

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

11.1K
A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
08:22

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Published on: December 1, 2017

8.7K

Related Experiment Videos

Last Updated: Oct 6, 2025

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome
05:12

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome

Published on: September 19, 2019

6.7K
Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
07:15

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

11.1K
A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
08:22

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Published on: December 1, 2017

8.7K

Area of Science:

  • Gastroenterology
  • Surgical Pathology

Background:

  • Wilkie's syndrome is a rare condition involving extrinsic compression of the third duodenal segment by the superior mesenteric artery (SMA).
  • Symptoms are often non-specific, including postprandial pain, nausea, vomiting, early satiety, anorexia, and weight loss, complicating diagnosis.
  • Contrast-enhanced CT is the standard imaging modality, with surgery reserved for severe or refractory cases.

Observation:

  • A 66-year-old woman presented with significant weight loss and symptoms suggestive of duodenal obstruction.
  • Imaging revealed duodenal distension and compression at D3 by the SMA.
  • Laboratory tests indicated acute renal failure and hypokalemia secondary to dehydration.

Findings:

  • A laparoscopic duodenojejunostomy was performed for Wilkie's syndrome.
  • The patient experienced an uneventful recovery and was discharged on postoperative day nine.
  • Postoperative imaging confirmed normal contrast progression through the gastrointestinal tract.

Implications:

  • Wilkie's syndrome is an often-overlooked cause of intestinal obstruction due to its vague symptoms.
  • High clinical suspicion is crucial for timely diagnosis.
  • Duodenojejunostomy is presented as a surgical option with favorable outcomes for managing Wilkie's syndrome.