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Published on: September 8, 2023
Giant Coronary Artery Aneurysm: A Successful Diagnosis
Michel El Khoury1, Viswajit Reddy Anugu2, Chadi Salmane3
1Internal Medicine, Northwell Health, New York, USA.
Insights
Giant coronary artery aneurysms (CAAs) are rare cardiovascular abnormalities. This case highlights a large right coronary artery aneurysm successfully treated with bypass surgery and resection, emphasizing early diagnosis for better outcomes.
Area of Science:
- Cardiology
- Vascular Surgery
- Pathology
Background:
- Coronary artery aneurysms (CAAs) are uncommon, with giant CAAs being exceedingly rare and potentially life-threatening cardiovascular conditions.
- The exact cause of CAAs remains unclear, necessitating further research into their pathophysiology.
- Current management strategies for CAAs lack evidence-based guidelines, leading to individualized treatment approaches.
Observation:
- A 74-year-old male presented with chest pain, exhibiting signs of myocardial ischemia on an adenosine thallium scan.
- Echocardiography revealed a giant aneurysm of the right coronary artery (RCA), measuring 5.6 × 7.5 cm.
- Coronary angiography confirmed the large RCA aneurysm and additional dilatations in the left anterior descending and circumflex arteries without significant stenosis.
Findings:
- Surgical intervention involved a reversed saphenous vein interposition graft from the ascending aorta to the right posterior descending artery.
- Pathological examination of the resected RCA aneurysm showed myxoid degeneration of the media and thrombus formation.
- The patient experienced no complications following the surgical procedure.
Implications:
- This case underscores the importance of early diagnosis of CAAs to prevent potentially fatal complications.
- Individualized therapeutic strategies are crucial due to the absence of established, evidence-based management protocols for CAAs.
- Further research is needed to elucidate the pathophysiology and establish standardized treatment guidelines for these rare vascular abnormalities.
Abstract:
Coronary artery aneurysms (CAAs) are rare, with giant CAAs being even rarer. The precise pathophysiology of this phenomenon is still unknown. CAAs are seldom reported life-threatening abnormalities of the cardiovascular system. We herein present a case of a 74-year-old man who presented at the hospital complaining of chest pain. An adenosine thallium scan revealed a small, reversible defect in the inferior wall of the left ventricle extending into the apex, consistent with ischemia. Echocardiography uncovered a large right coronary artery (RCA) aneurysm, measuring 5.6 × 7.5 cm. Diagnostic coronary angiography confirmed the presence of a large RCA aneurysm and aneurysmal dilation of the left anterior descending and circumflex arteries with no flow-limiting lesions. A reversed saphenous vein interposition graft was placed from the ascending aorta to the right posterior descending artery. The RCA aneurysmal sac was resected and sent to pathology, which uncovered myxoid degeneration of the media as well as thrombus formation. No complications were encountered during the procedure. Early diagnosis is vital to avoid fatal complications of CAAs, and therapeutic approaches are currently individualized in view of absence of evidence-based management strategies.
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