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Ventricular fibrillation and sudden cardiac arrest in apical hypertrophic cardiomyopathy: Two case reports

Yae Min Park1, Albert Youngwoo Jang2, Wook-Jin Chung2

  • 1Department ofCardiology, Gachon University Gil Medical Center, Incheon 21556, South Korea. ypruimin@gmail.com.

World Journal of Clinical Cases
|January 20, 2022
PubMed

Insights

Apical hypertrophic cardiomyopathy (HCM) can lead to sudden cardiac death (SCD) and ventricular fibrillation (VF). These cases highlight the need for careful consideration of implantable cardioverter-defibrillator (ICD) therapy in affected patients.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Genetics

Background:

  • Apical hypertrophic cardiomyopathy (HCM) is typically associated with a favorable prognosis regarding cardiovascular mortality.
  • However, this case series focuses on the underrecognized risk of ventricular fibrillation (VF) and sudden cardiac death (SCD) in apical HCM.

Observation:

  • Two patients with apical HCM experienced documented VF and sudden cardiac collapse.
  • Neither patient met current guidelines for primary prevention with an implantable cardioverter-defibrillator (ICD).

Findings:

  • These cases demonstrate that apical HCM can present with life-threatening arrhythmias like VF and aborted SCD.
  • Current guidelines may not adequately identify all apical HCM patients at risk for these severe events.

Implications:

  • These findings suggest a need to re-evaluate risk stratification for SCD in apical HCM.
  • Consideration of ICD implantation for secondary prevention is crucial in these high-risk patients.
Abstract

Keywords:
Apical hypertrophic cardiomyopathyCase reportImplantable cardioverter-defibrillatorVentricular fibrillation

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