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US Hospital Stays in Children and Adolescents With Acetaminophen Poisoning

Kristin A Shadman1, M Bruce Edmonson1, Ryan J Coller1

  • 1Departments of Pediatrics.

Hospital Pediatrics
|January 20, 2022
PubMed

Insights

Acetaminophen poisoning led to over 9,900 hospitalizations in U.S. children in 2016. This common poisoning in adolescents highlights the need for enhanced prevention strategies to reduce hospital stays.

Area of Science:

  • Pediatrics
  • Toxicology
  • Public Health

Background:

  • Acetaminophen poisoning is a significant health concern across all age groups.
  • Hospital-based outcomes for pediatric acetaminophen poisoning require further characterization.
  • Understanding intentionality is crucial for effective intervention.

Purpose of the Study:

  • To determine the incidence and characteristics of hospital stays for acetaminophen poisoning in children.
  • To analyze the outcomes of pediatric acetaminophen poisoning hospitalizations.
  • To evaluate the role of intentionality in these poisonings.

Main Methods:

  • Utilized the 2016 Kids' Inpatient Database for hospitalization data.
  • Employed validated International Classification of Diseases, 10th Revision (ICD-10) codes.
  • Applied standard survey methods for weighted population estimates and outcome analysis, stratified by intentionality.

Main Results:

  • In 2016, there were 9,935 hospitalizations for acetaminophen poisoning in U.S. children (0-19 years).
  • Acetaminophen was the most frequent agent in self-harm medication poisonings among children.
  • Nearly half of discharges were transferred to other facilities, indicating complex care needs.

Conclusions:

  • Acetaminophen poisoning represents a leading cause of U.S. pediatric hospitalizations for medication self-harm.
  • There is a critical need for improved prevention strategies targeting acetaminophen poisoning in adolescents.
  • Reducing the incidence of this common malady requires focused public health interventions.
Abstract

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