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[Pulmonology 2021: year in review]
Caroline Rayroux1, Frédéric Lador1, Paola M Soccal1
1Service de pneumologie, Département de médecine, Hôpitaux universitaires de Genève, 1211 Genève 14.
Revue Medicale Suisse
|January 20, 2022
Summary
New pulmonology treatments in 2021 include biotherapy for severe asthma and improved pulmonary arterial hypertension management with upfront triple therapy. Transbronchial cryobiopsies offer a safer alternative for diagnosing interstitial lung diseases.
Area of Science:
- Pulmonology
- Therapeutic Developments
- Respiratory Medicine
Background:
- Review of significant advancements in pulmonary medicine during 2021.
- Focus on novel treatments for severe asthma and pulmonary arterial hypertension (PAH).
- Exploration of diagnostic techniques for diffuse interstitial lung diseases.
Purpose of the Study:
- To highlight key therapeutic breakthroughs in pulmonology from 2021.
- To discuss the clinical implications of new biotherapies and treatment strategies.
- To evaluate the role of transbronchial cryobiopsies in diagnosing interstitial lung diseases.
Main Methods:
- Literature review of recent publications and clinical trial data.
- Analysis of therapeutic efficacy and patient outcomes for selected conditions.
- Assessment of diagnostic accuracy and safety profiles of new procedures.
Main Results:
- A new biotherapy is available for severe uncontrolled non-Th2 asthma.
- Upfront triple therapy improves survival in high-risk pulmonary arterial hypertension patients.
- Transbronchial cryobiopsies are a viable alternative to surgical lung biopsy for interstitial lung disease diagnosis.
Conclusions:
- Significant progress has been made in managing severe asthma and pulmonary arterial hypertension.
- Emerging therapies like sotatercept show promise for group 1 PAH.
- Transbronchial cryobiopsy represents a less invasive diagnostic option for interstitial lung diseases.
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