Related Experiment Video

Updated: Oct 6, 2025

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
10:28

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function

Published on: March 15, 2022

5.3K

[Perioperative Antiplatelet Therapy in Patients with Coronary Stents Undergoing Elective Non-Cardiac Surgery]

Yi-Jun Liu1, Jin Liu1

  • 1Anesthesia & Operation Center, West China Hospital, Sichuan University, Chengdu 610041, China.

Sichuan Da Xue Xue Bao. Yi Xue Ban = Journal of Sichuan University. Medical Science Edition
|January 20, 2022
PubMed

Insights

Patients with coronary stents undergoing non-cardiac surgery face high risks of thrombosis and bleeding. Optimizing antiplatelet therapy is crucial for their perioperative safety and reducing complications.

Area of Science:

  • Cardiology
  • Anesthesiology
  • Perioperative Medicine

Background:

  • Patients with coronary stents are an increasing group undergoing elective non-cardiac surgery (NCS).
  • These patients have dual risks of thrombosis and bleeding due to stent implants and antiplatelet agents.
  • Managing perioperative antiplatelet therapy is essential for patient safety.

Purpose of the Study:

  • To review and analyze perioperative antiplatelet therapy strategies for patients with coronary stents undergoing NCS.
  • To discuss the dual risks of thrombosis and bleeding in this patient population.
  • To identify prospective research directions in perioperative antiplatelet management.

Main Methods:

  • Literature review and analysis of existing studies on perioperative antiplatelet therapy.
  • Examination of risks associated with coronary stents and antiplatelet agents in NCS.
  • Discussion of current guidelines and challenges in managing these patients.

Main Results:

  • Elective non-cardiac surgery patients with coronary stents present significant perioperative challenges.
  • Balancing the risks of stent thrombosis and surgical bleeding requires careful antiplatelet management.
  • Evidence-based strategies are needed to guide therapeutic decisions.

Conclusions:

  • Optimizing perioperative antiplatelet therapy is critical for reducing risks in patients with coronary stents undergoing NCS.
  • Further research is needed to establish definitive guidelines for managing these complex patients.
  • Personalized approaches to antiplatelet therapy are essential for ensuring patient safety.

Keywords:
Antiplatelet therapyCoronary stentsNon-cardiac surgery

More Related Videos

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis04:30

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

25.7K
Ferromagnetic Bare Metal Stent for Endothelial Cell Capture and Retention11:01

Ferromagnetic Bare Metal Stent for Endothelial Cell Capture and Retention

Published on: September 18, 2015

11.7K

Related Concept Videos

Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors01:20

Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors

Antiplatelet drugs emerge as frontline defenders against the insidious threat of thromboembolic diseases, where abnormal clots obstruct vital blood vessels. These drugs stand as bulwarks, inhibiting platelet aggregation and clot formation, thereby mitigating the risk of life-threatening conditions like myocardial infarction, coronary artery disease, and thrombotic strokes.
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
701
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
45
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
58
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
46
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
43
Angina IV: Management01:26

Angina IV: Management

IntroductionThe management of angina requires a comprehensive approach that includes pharmacological therapies, medical procedures, and lifestyle modifications.Pharmacological TherapiesAntiplatelet agents, such as aspirin, clopidogrel, prasugrel, and ticagrelor, play a pivotal role in preventing thrombus formation in patients with angina. These medications inhibit platelet aggregation and reduce the likelihood of myocardial infarction and other cardiovascular events.Anticoagulants, including...
43