Related Experiment Video
Updated: Oct 6, 2025
Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
[The Effect of Interventional Treatment with Bronchoscopy in 10 Children with Acquired Subglottic Stenosis]
Guang-Li Zhang1, Chong-Jie Wang1, Shuai Peng1
1Department of Respiratory Medicine, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Key Laboratory of Child Development and Disorders of the Ministry of Education, and Chongqing Key Laboratory of Pediatrics, Chongqing 400014, China.
Insights
Bronchoscopic interventional therapy, including balloon dilatation and laser treatments, effectively treats acquired subglottic stenosis (SGS) in children. Follow-up assessments confirm varying degrees of improvement in SGS after these procedures.
Area of Science:
- Pediatric Pulmonology
- Interventional Bronchoscopy
- Pediatric Airway Disorders
Background:
- Acquired subglottic stenosis (SGS) poses a significant challenge in pediatric respiratory care.
- Effective treatment options for pediatric acquired SGS are crucial for improving patient outcomes.
Purpose of the Study:
- To evaluate the efficacy of interventional bronchoscopic therapies for acquired subglottic stenosis in pediatric patients.
- To assess the outcomes of treatments such as balloon dilatation, holmium laser, and cryotherapy.
Main Methods:
- Retrospective analysis of clinical data from ten pediatric inpatients with acquired SGS.
- Inclusion of follow-up data at 1 week, 1 month, 3 months, and 6 months post-procedure.
- Examination of interventional techniques including balloon dilatation, holmium laser, and cryotherapy.
Main Results:
- Ten pediatric patients (5 boys, 5 girls; median age 11 months) with acquired SGS were treated.
- Successful outcomes were observed with both standalone balloon dilatation and comprehensive therapies (balloon dilatation, laser, cryotherapy).
- Bronchoscopy confirmed improvement in SGS in most patients, although one case resulted in fatal airway obstruction.
Conclusions:
- Interventional bronchoscopy demonstrates effectiveness in managing acquired subglottic stenosis in children.
- A range of bronchoscopic techniques can be employed to address pediatric acquired SGS.
- Further research may refine treatment protocols for optimal pediatric SGS management.
Objective:
To explore the effects of interventional therapy with bronchoscopy in children with acquired subglottic stenosis (SGS).
Methods:
The clinical data of ten pediatric inpatients with acquired SGS who were admitted to Children's Hospital of Chongqing Medical University, as well as their follow-up information obtained 1 week, 1 month, 3 months and 6 months after the procedure was done.were retrospectively analyzed to examine the effect of interventional bronchoscopic therapies, including balloon dilatation, holmium laser, and cryotherapy, in pediatric patients with acquired SGS.
Results:
Among the 10 patients with acquired SGS, there were 5 boys and 5 girls aged between 1 month and 6 years and 5 months, with a median age of 11 months and 1 day. Among the 5 patients with acute acquired SGS, two were treated with balloon dilatation only, with one cured and one showing clinical improvement, while three received comprehensive interventional therapy combining balloon dilatation, holmium laser, and cryotherapy, with two cured and one showing improvement. Among the 5 patients with chronic acquired SGS, four cases were cured with comprehensive interventional therapy, while one case suffered from aggravated upper airway obstruction 4 + hours after balloon dilatation. The patient was subsequently put on invasive mechanical ventilation for 4 days, but was unable to be extubated. The parents signed do-not-resuscitate order and the patient died afterwards. Bronchoscopy performed 1 week, 1 month and 3 months after the procedure was done showed that the SGS was improved to varying degrees.
Conclusion:
Bronchoscopy intervention is an effective therapy for acquired SGS in children.
Related Concept Videos
01:22Trachea
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
01:30Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques
01:30Endoscopic Studies I: Bronchoscopy and Thoracoscopy
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
01:26Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
01:26COPD: Management Using Bronchodilators and Corticosteroids
01:30Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...