Subthreshold post-traumatic stress disorder as a risk factor for post-traumatic stress disorder: results from a

Robert H Pietrzak1, Frances G Javier1, John H Krystal1

  • 1US Department of Veterans Affairs National Center for Posttraumatic Stress Disorder, VA Connecticut Healthcare System, Connecticut, USA; and Department of Psychiatry, Yale School of Medicine, Connecticut, USA.

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Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
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