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Human Amniotic Membrane Plug for Chronic or Persistent Macular Holes
Mark D Bamberger1, Tina Felfeli2, Michael Politis3
1Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.
Purpose:
To report on the use of human amniotic membrane for macular holes at 2 Canadian tertiary care centers.
Design:
Retrospective cohort study.
Subjects:
Twenty-two patients with persistent or chronic macular holes.
Methods:
Macular hole surgery was performed by 3 vitreoretinal surgeons.
Main Outcome Measures:
Macular hole closure with complete plugging by human amniotic membrane on spectral-domain OCT.
Results:
The closure rate was 91% (20 of 22; median follow-up, 7 months), with no statistically significant visual acuity change overall. Complications included subretinal silicone oil (5%), choroidal neovascularization (5%), atrophy (5%), and cystoid macular edema (9%).
Conclusions:
Anatomical success with limited visual recovery was observed.
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