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Peripheral Nerve Stimulation: The Evolution in Pain Medicine.

Alaa Abd-Elsayed1, Ryan S D'Souza2

  • 1Department of Anesthesiology, University of Wisconsin, Madison, WI 53711, USA.

Biomedicines
|January 21, 2022
PubMed
Summary

Electrical stimulation of peripheral nerves offers therapeutic benefits for various conditions. This technology has been refined over fifty years for improved patient outcomes.

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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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