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Aripiprazole-Induced Oculogyric Crisis: A Pediatric Case Series and A Brief Narrative Review
Pia Bernardo1, Alfonso Rubino2, Claudia Santoro3,4
1Department of Neurosciences, Pediatric Psychiatry and Neurology, Santobono-Pausilipon Children's Hospital, 80120 Naples, Italy.
Abstract:
Oculogyric crisis (OGC) represent an unusual type of dystonic movement disorder, usually reported as an adverse event of antipsychotic drugs, with acute or tardive onset, likely due to a functional disruption of dopaminergic neurotransmission. It is seldom reported in children with aripiprazole, an atypical antipsychotic commonly used in youths. In this manuscript, we report on a case series of three pediatric patients and provide a brief narrative review of the literature, in order to increase the awareness of clinicians and to foster future research in this area.
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