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Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS
Published on: April 7, 2021
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Evidence-Based Mechanical Ventilatory Strategies in ARDS.
Adnan Liaqat1, Matthew Mason2, Brian J Foster1
1Southeast Health, Dothan, AL 36301, USA.
Journal of Clinical Medicine
|January 21, 2022
Summary
Mechanical ventilation strategies, including low tidal volumes and prone positioning, are crucial for managing acute respiratory distress syndrome (ARDS). This review examines evidence-based approaches to improve outcomes in critically ill patients with ARDS.
Area of Science:
- Critical Care Medicine
- Pulmonology
- Respiratory Physiology
Background:
- Acute respiratory distress syndrome (ARDS) is a significant cause of death in critically ill patients.
- Mechanical ventilation is essential for managing ARDS and preventing further lung injury.
Purpose of the Study:
- To review evidence-based mechanical ventilatory strategies for ARDS.
- To discuss ventilatory adjuncts and their role in ARDS management.
Main Methods:
- Review of existing literature on mechanical ventilation in ARDS.
- Analysis of evidence for various ventilatory strategies and adjuncts.
Main Results:
- Low tidal volumes, low plateau pressures, low fraction of inspired oxygen (FiO2), optimized positive end-expiratory pressure (PEEP), and prone ventilation reduce ARDS morbidity and mortality.
- The efficacy of non-invasive ventilation, recruitment maneuvers, esophageal pressure monitoring, and extracorporeal support in ARDS requires further clarification.
Conclusions:
- Established mechanical ventilation strategies are vital for improving ARDS patient outcomes.
- Further research is needed to clarify the role of emerging ventilatory strategies and adjuncts in ARDS management.
Keywords:
ARDSECMOPEEPacute respiratory distress syndromelung recruitmentmechanical ventilation strategiesnoninvasive ventilationMore Related Videos
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