Related Experiment Video
Updated: Oct 6, 2025

A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration
Published on: February 27, 2018
Does Preoperative Cognitive Optimization Improve Postoperative Outcomes in the Elderly?
1Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Preoperative brain exercise may reduce postoperative delirium in elderly patients. Further research is needed to establish effective cognitive training programs for presurgical optimization to prevent perioperative neurocognitive disorder (PND).
Area of Science:
- Geriatric Medicine
- Neuroscience
- Surgical Outcomes
Background:
- Perioperative neurocognitive disorder (PND) is a significant concern for millions of elderly patients annually.
- Effective prevention strategies for PND are currently lacking.
- Preoperative cognitive optimization shows promise for improving postoperative cognitive function.
Purpose of the Study:
- To review current knowledge on preoperative cognitive optimization for preventing PND.
- To highlight landmark and ongoing studies in this rapidly evolving field.
- To discuss the role of cognitive training in elderly populations, including those with cognitive impairment.
Main Methods:
- Literature review of studies on preoperative cognitive optimization.
- Examination of preclinical evidence related to cognitive training and brain plasticity.
- Analysis of studies on cognitive training in non-surgical elderly and those with dementia.
Main Results:
- Preoperative brain exercise has been shown to decrease postoperative delirium incidence in elderly surgical patients.
- Cognitive training demonstrates benefits in non-surgical elderly populations.
- Preclinical evidence supports cognitive training's role in understanding brain plasticity and PND pathophysiology.
Conclusions:
- Presurgical cognitive optimization shows positive impacts on postoperative cognitive outcomes.
- Further studies are essential to develop and validate effective cognitive training programs for elderly presurgical patients.
- The field of cognitive optimization for PND prevention is rapidly expanding.
More Related Videos
13:12Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
Published on: August 12, 2019
06:28E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
Published on: August 1, 2019
Related Concept Videos
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Pharmacodynamics in Geriatric Patients: Effects of Age
Peripheral Artery Disease V: Postoperative Nursing Management
Drug Dosing: Geriatric Patients
Cognitive Development During Adulthood
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism