Related Experiment Video
Updated: Jul 26, 2026

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
Published on: June 7, 2015
Crosslinking-Dependent Drug Kinetics in Hydrogels for Ophthalmic Delivery
Nicole Mortensen1, Parker Toews1, Jeffrey Bates1
1Department of Materials Science and Engineering, University of Utah, 122 Central Campus Drive, Room 304, Salt Lake City, UT 84112, USA.
Abstract:
Drug-diffusion kinetics in 2-hydroxyethyl methacrylate hydrogels were studied as a function of the crosslinking density and porosity. By varying the concentration of the crosslinker, tetraethylene glycol dimethacrylate, we demonstrated how the release of Timolol maleate could be optimized to allow for efficient drug delivery. FTIR and spectrophotometry supplied optical inferences into the functional groups present. By studying the swelling and degradation of hydrogels, supplemented with drug-release kinetics studies, the relationship between these two tenets could be formulated.
More Related Videos
Related Concept Videos
Modified-Release Drug Delivery Systems: Rate-Programmed II
Modified-Release Drug Delivery Systems: Stimuli-Activated
Modified-Release Drug Delivery Systems: Site-Targeted
Site-Targeted Drug Delivery Systems: Polymeric Carriers
Oral Drug Delivery Systems: Delayed-Release Systems
Ophthalmic Drug Delivery Systems

