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Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
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Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
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Nuclear Imaging in Infective Endocarditis.

Nidaa Mikail1,2,3, Fabien Hyafil4

  • 1Department of Nuclear Medicine, Beaujon University Hospital, Assistance Publique-Hôpitaux de Paris, 100 Boulevard du Général Leclerc, 92110 Clichy, France.

Pharmaceuticals (Basel, Switzerland)
|January 21, 2022
PubMed
Summary
This summary is machine-generated.

Diagnosing infective endocarditis (IE) is challenging, especially for prosthetic valves and cardiac implanted electronic devices (CIEDs). Nuclear imaging techniques like 18F-FDG-PET/CT and WBC-SPECT offer valuable insights for IE management.

Keywords:
18F-FDGcardiac implanted electronic deviceinfective endocarditisleft ventricular assistance devicenative valve endocarditisnuclear medicinepositron emission tomographyprosthetic valve endocarditisscintigraphyvascular graft infectionwhite blood cell scintigraphy

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Area of Science:

  • Cardiology
  • Nuclear Medicine
  • Infectious Diseases

Background:

  • Infective endocarditis (IE) remains a serious condition despite medical advancements.
  • Increasing use of cardiac devices leads to a rise in IE cases involving prosthetic valves and CIEDs.
  • Current diagnostic criteria (Duke-Li) face challenges, particularly in complex cases.

Purpose of the Study:

  • To review nuclear imaging techniques for IE diagnosis.
  • To discuss the application of 18F-FDG-PET/CT and WBC-SPECT in prosthetic valve and CIED IE.
  • To evaluate the diagnostic performance and integration of these techniques into IE algorithms.

Main Methods:

  • Review of current literature on IE diagnosis.
  • Summary of image acquisition protocols for 18F-FDG-PET/CT and WBC-SPECT.
  • Analysis of diagnostic performance data for nuclear imaging in IE.

Main Results:

  • Echocardiography is primary for native valve endocarditis.
  • 18F-FDG-PET/CT and WBC-SPECT show significant value in prosthetic valve and CIED IE.
  • These nuclear techniques enhance diagnostic accuracy in specific IE scenarios.

Conclusions:

  • Nuclear imaging, specifically 18F-FDG-PET/CT and WBC-SPECT, plays a crucial role in diagnosing IE, particularly with cardiac devices.
  • Integrating these advanced imaging modalities improves diagnostic algorithms for suspected IE.
  • Further research and standardized protocols can optimize their use in clinical practice.