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Updated: Oct 6, 2025

Optical Detection of E. coli Bacteria by Mesoporous Silicon Biosensors
Published on: November 20, 2013
Passivated Porous Silicon Membranes and Their Application to Optical Biosensing
Clara Whyte Ferreira1, Roselien Vercauteren1, Laurent A Francis1
1Institute of Information and Communication Technologies, Electronics, and Applied Mathematics, UCLouvain, 1348 Louvain-la-Neuve, Belgium.
Abstract:
A robust fabrication method for stable mesoporous silicon membranes using standard microfabrication techniques is presented. The porous silicon membranes were passivated through the atomic layer deposition of different metal oxides, namely aluminium oxide Al2O3, hafnium oxide HfO2 and titanium oxide TiO2. The fabricated membranes were characterized in terms of morphology, optical properties and chemical properties. Stability tests and optical probing noise level determination were also performed. Preliminary results using an Al2O3 passivated membranes for a biosensing application are also presented for selective optical detection of Bacillus cereus bacterial lysate. The biosensor was able to detect the bacterial lysate, with an initial bacteria concentration of 106 colony forming units per mL (CFU/mL), in less than 10 min.

