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Polysaccharide 3D Printing for Drug Delivery Applications
Alexandra Zamboulis1, Georgia Michailidou1, Ioanna Koumentakou1
1Laboratory of Chemistry and Technology of Polymers and Dyes, Department of Chemistry, Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece.
Pharmaceutics
|January 21, 2022
Summary
This review explores 3D printing of polysaccharides for personalized drug delivery. Key polysaccharides like cellulose and chitosan are discussed for pharmaceutical applications, addressing a gap in current literature.
Area of Science:
- Pharmaceutical Science
- Materials Science
- Biotechnology
Background:
- 3D printing offers design versatility and material choice for personalized medicine.
- Polysaccharides are biocompatible, biodegradable natural polymers widely used in pharmaceuticals.
- A gap exists in reviews focusing on 3D printing of polysaccharides for drug delivery.
Purpose of the Study:
- To review recent advances in 3D printing of polysaccharides for drug delivery applications.
- To highlight the potential of 3D printed polysaccharide matrices in personalized pharmaceutical treatments.
- To focus on specific polysaccharides like cellulose, chitosan, and sodium alginate.
Main Methods:
- Review of recent scientific literature on 3D printing and polysaccharide-based drug delivery.
- Focus on fused deposition modeling and extrusion-based printing techniques.
- Analysis of polysaccharide properties relevant to additive manufacturing.
Main Results:
- Polysaccharides show promise as matrices for 3D printed drug delivery systems.
- Cellulose, chitosan, and sodium alginate are key candidates for 3D printing.
- Fused deposition modeling and extrusion-based printing are viable methods for polysaccharide fabrication.
Conclusions:
- 3D printing of polysaccharides is a developing field with significant potential for personalized drug delivery.
- Further research into optimizing polysaccharide formulations and printing parameters is warranted.
- This review addresses the need for focused information on 3D printed polysaccharides in pharmaceutical applications.
Keywords:
alginatecellulosechitosancontrolled drug releasedrug deliveryextrusion-based printingfused deposition modelinghydrogelspersonalized medicine
