Clinical and Laboratory Profile of Dengue in Kashmir Valley

As majority of cases of dengue are associated with thrombocytopenia, it is indispensable to study clinical presentation, biochemical parameters and outcome of dengue fever in a population known with low platelet count.

A prospective observational study was conducted from September 2016 to August 2017that included forty NS-1 antigen (IgM) Dengue positive patients. Clinical features, laboratory parameters and outcome of dengue patients were noted.

All the patients had travel history outside the valley into the neighbouring state. Most patients (70%) had duration of stay between 21-30 days in dengue prevalent areas before catching the illness. Duration of symptoms was between 4-9 days in majority of patients (92.5%). Most patients (85%) presented in months of September to November. The three most common symptoms were fever (100%), chills (92.5%) and headache (80%). The most common laboratory features were thrombocytopenia (97.5%), leukopenia (87.5%), transaminitis (87.5%) and raised LDH (32.5%). One patient developed Dengue Hemorrhagic Fever (DHF). All patients recovered completely.

DF in Kashmir is seen exclusively in travellers to other states especially in the monsoon season.DF in Kashmiri patients has a favourable outcome despite low baseline platelet count. DHF is uncommon in Kashmiri population.