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Laboratory Administration of Transcutaneous Auricular Vagus Nerve Stimulation taVNS: Technique, Targeting, and Considerations
Published on: January 7, 2019
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Closed-Loop Transcutaneous Auricular Vagal Nerve Stimulation: Current Situation and Future Possibilities
Yutian Yu1,2, Jing Ling3, Lingling Yu4
1Acupuncture Department, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Frontiers in Human Neuroscience
|January 21, 2022
Summary
Closed-loop transcutaneous auricular vagal nerve stimulation (CL-taVNS) offers new therapeutic possibilities. This review outlines existing systems and proposes future directions for CL-taVNS development.
Area of Science:
- Neuroscience
- Biomedical Engineering
- Medical Devices
Background:
- Closed-loop transcutaneous auricular vagal nerve stimulation (CL-taVNS) emerged in 2020.
- Existing systems include motor-activated (MAAVNS) and respiratory-gated (RAVANS) approaches.
- Vagal nerve stimulation is a promising therapeutic modality.
Purpose of the Study:
- To review current CL-taVNS systems.
- To propose novel future CL-taVNS systems.
- To outline mechanisms, targets, and technical challenges in CL-taVNS.
Main Methods:
- Literature review of existing CL-taVNS.
- Proposal of new CL-taVNS systems based on EEG, ECG, and SHS.
- Analysis of technical aspects and stimulation patterns.
Main Results:
- Two primary forms of CL-taVNS (MAAVNS, RAVANS) were reviewed.
- Three future CL-taVNS systems were proposed: EEG-gated, ECG-gated, and SHS-gated.
- Key considerations for CL-taVNS development were highlighted.
Conclusions:
- This work provides a foundational blueprint for advancing CL-taVNS.
- Future research should focus on the proposed EEG, ECG, and SHS-gated systems.
- Understanding mechanisms and technical issues is crucial for CL-taVNS innovation.
