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[Clinical approach for periocular lymphoma]
Michael Simon1, Philomena A Wawer Matos1, Jörn Meinel2
1Zentrum für Augenheilkunde, Universität zu Köln, Medizinische Fakultät und Uniklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Background:
Lymphomas occur very frequently in the periocular region, predominantly in adulthood. This malignant tumor shows a heterogeneous clinical pattern.
Aim:
The aim of this article is to provide an overview of the symptoms, diagnostic procedures and treatment options for lymphomas of the periocular region.
Symptoms:
The symptoms of periocular lymphomas are mostly nonspecific. The growth is usually painless and slowly progressive. A salmon-colored swelling is typical for conjunctival lymphoma.
Diagnostics:
The basis of a precise diagnostic process is a detailed anamnesis. Contrast-enhanced magnetic resonance imaging (MRI) is considered the gold standard for imaging of lymphoproliferative lesions. A histopathological examination should be carried out to confirm the exact diagnosis. Subsequently, staging should be performed as periocular lymphomas can be the manifestation of a systemic involvement.
Treatment:
The treatment procedure should be coordinated by an interdisciplinary tumor board. The treatment of periocular lymphomas can include percutaneous stereotactic irradiation as well as chemotherapeutic or new immunotherapeutic strategies.
