Long-term renal outcome post-multimodal computed tomography in stroke evaluation.

Area of Science:

• Nephrology
• Neurology
• Radiology

Background:

• Contrast-associated acute kidney injury (CA-AKI) is a potential complication following imaging procedures.
• Recent studies suggest a low risk of CA-AKI after multimodal computed tomography (MMCT) for acute stroke evaluation.
• Long-term renal outcomes after MMCT in stroke patients require further investigation.

Purpose of the Study:

• To evaluate the incidence of CA-AKI in patients undergoing MMCT for suspected stroke.
• To assess the long-term renal function and outcomes in these patients.
• To determine the safety profile of MMCT regarding renal health in stroke evaluation.

Main Methods:

• Retrospective analysis of suspected stroke cases undergoing MMCT (CTA, CTP, or both) between January 2019 and June 2020.
• Inclusion criteria focused on patients with available renal follow-up data.
• Calculation of CA-AKI incidence and assessment of renal function at >30 days post-MMCT.

Main Results:

• The incidence of CA-AKI was 7.6% (18/238 cases).
• All identified CA-AKI cases were associated with pre-existing renal confounders.
• No acute kidney injury (AKI) was observed in 60.5% (144/238) of cases at >30 days post-MMCT.

Conclusions:

• The incidence of CA-AKI following MMCT for stroke evaluation is low.
• The presence of renal confounders is a significant factor in CA-AKI development.
• Long-term renal outcomes appear favorable (>30 days) after MMCT in stroke patients, suggesting a good safety profile.