Related Experiment Video

Updated: Oct 6, 2025

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
06:45

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis

Published on: February 10, 2023

14.5K

Risk assessment of venous thromboembolism and bleeding in COVID-19 patients

Lan Wang1,2, Lan Zhao1,3, Feng Li1

  • 1Department of Respirology, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.

The Clinical Respiratory Journal
|January 21, 2022
PubMed

Insights

Critically ill COVID-19 patients face high risks of both blood clots (venous thromboembolism) and bleeding. Individualized prevention strategies are crucial for managing these risks in severe cases.

Area of Science:

  • Medicine
  • Cardiology
  • Infectious Diseases

Background:

  • Coronavirus disease 2019 (COVID-19) is a global pandemic.
  • Increasing evidence links COVID-19 with heightened risks of venous thromboembolism (VTE).
  • This study evaluates in-hospital VTE and bleeding risks in COVID-19 patients.

Purpose of the Study:

  • To identify in-hospital venous thromboembolism (VTE) risk.
  • To identify in-hospital bleeding risk.
  • To analyze clinical features of VTE patients.

Main Methods:

  • Retrospective study of 138 COVID-19 patients.
  • Utilized Padua Prediction Score for VTE risk assessment.
  • Employed Improve bleed risk assessment model for bleeding risk.

Main Results:

  • 16.7% of patients had high VTE risk; 6.5% had high bleeding risk.
  • Critically ill patients (15) faced dual high risks for thrombosis and hemorrhage.
  • VTE occurred in 2.9% of all patients (20% of critically ill); one major hemorrhage during treatment.

Conclusions:

  • Critically ill COVID-19 patients exhibit high risks for both thrombosis and bleeding.
  • Individualized bleeding risk assessment is vital for effective VTE prevention in severe cases.
  • Enhanced VTE prevention strategies are needed for critically ill COVID-19 patients.
Abstract

Keywords:
Padua prediction scorecoronavirus disease 2019deep vein thrombosisimprove bleed risk assessment modelvenous thromboembolism

More Related Videos

Author Spotlight: Advancing Cancer Associated Thrombosis Research in Rodent Models04:40

Author Spotlight: Advancing Cancer Associated Thrombosis Research in Rodent Models

Published on: January 5, 2024

2.7K
Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation06:04

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation

Published on: August 8, 2025

223

Related Concept Videos

Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
42
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
46
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
62
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
55
Disorders of Hemostasis01:24

Disorders of Hemostasis

Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
1.3K
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
168