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Updated: Oct 6, 2025

Mouse Kidney Transplantation: Models of Allograft Rejection
Published on: October 11, 2014
Paradoxical Perforating Folliculitis in a Newly Transplanted Kidney Recipient: Case Study
Onke R Nonkala1,2, Mahomed I Haffejee, Marius van der Walt
1From the Department of Nephrology Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.
A rare case of perforating folliculitis presented paradoxically in an 18-year-old kidney transplant patient. The skin condition, initially misdiagnosed as chickenpox, resolved with immunosuppressive therapy post-transplant.
Area of Science:
- Dermatology
- Nephrology
- Transplantation
Background:
- End-stage kidney failure necessitates renal replacement therapy, including dialysis and transplantation.
- Immunosuppressive therapy is crucial post-kidney transplant to prevent organ rejection.
Observation:
- An 18-year-old patient on continuous ambulatory peritoneal dialysis developed a papular eruption initially misdiagnosed as chickenpox.
- Post-kidney transplant, the patient presented with a similar eruption, confirmed as perforating folliculitis via skin biopsy.
Findings:
- Perforating folliculitis is a rare skin condition presenting as papules on an erythematous base.
- The patient's skin lesions resolved with immunosuppressive treatment (prednisone and tacrolimus) following kidney transplantation.
Implications:
- This case highlights a paradoxical presentation of perforating folliculitis in an immunosuppressed patient.
- Effective management of immunosuppression may lead to resolution of certain dermatological conditions post-transplant.
Related Concept Videos
Kidney Transplant II: Surgical Procedure
Kidney Transplant III: Nursing Management
Kidney Transplant I: Introduction
Acute Pyelonephritis II: Diagnostic Studies and Management
Acute Pyelonephritis I: Introduction
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

