Survival probability during one-year follow-up after index hospitalization for heart failure: an Italian

S Romano1, A Dante1, L Mammarella2

  • 1Department of Health, Life, and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.

Insights

Older patients with heart failure (HF) and longer hospital stays face higher mortality risk. Early discharge home and higher education improve survival chances in HF patients.

Area of Science:

  • Cardiology
  • Public Health
  • Geriatrics

Background:

  • Heart failure (HF) affects 64 million globally, with high mortality despite resource allocation.
  • Investigating patient characteristics is crucial for improving HF prognosis.

Purpose of the Study:

  • To analyze the impact of patient characteristics on survival probability after heart failure hospitalization.
  • To identify key factors influencing one-year survival post-discharge for heart failure patients.

Main Methods:

  • Retrospective study of 1,929 patients hospitalized for heart failure.
  • One-year follow-up data collected post-discharge for survival analysis.

Main Results:

  • 14% of patients died within one year; 50% of these deaths occurred within three months.
  • Age ≥75 years (HR 3.19), longer index hospitalization ≥8 days (HR 1.53), and discharge not to home (HR 0.399) were associated with lower survival.
  • Higher education level (HR 0.517) was linked to improved survival.

Conclusions:

  • Older patients, particularly those with lower education and longer hospital stays, require enhanced post-discharge care.
  • Discharge destination significantly impacts heart failure patient survival.
  • Identifying at-risk patients early can guide targeted interventions to improve heart failure outcomes.
Abstract

Related Concept Videos

Actuarial Approach01:20

Actuarial Approach

The actuarial approach, a statistical method originally developed for life insurance risk assessment, is widely used to calculate survival rates in clinical and population studies. This method accounts for participants lost to follow-up or those who die from causes unrelated to the study, ensuring a more accurate representation of survival probabilities.
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
146
Assumptions of Survival Analysis01:15

Assumptions of Survival Analysis

Survival models analyze the time until one or more events occur, such as death in biological organisms or failure in mechanical systems. These models are widely used across fields like medicine, biology, engineering, and public health to study time-to-event phenomena. To ensure accurate results, survival analysis relies on key assumptions and careful study design.
215
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
65
Heart Failure I: Introduction01:27

Heart Failure I: Introduction

Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
109
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.9K
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
92