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Updated: Sep 21, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
The epidemiology of childhood eczema: II. Statistical analyses to identify independent early predictors
1Department of Medical Computing and Statistics, University of Wales College of Medicine, Cardiff.
Insights
Maternal history of allergies and higher parental education are key predictors of childhood eczema. Originating from the West Indies or Africa also increased risk in this UK birth cohort study.
Area of Science:
- Epidemiology
- Pediatrics
- Dermatology
Background:
- Childhood eczema affects a significant portion of the population.
- Identifying early predictors is crucial for understanding disease etiology and prevention.
Purpose of the Study:
- To identify independent early predictors of childhood eczema.
- To analyze risk factors in a nationally representative UK birth cohort.
Main Methods:
- Analysis of data from a nationally representative sample of singletons born in April 1970.
- Utilized birth and five-year follow-up survey data for 11,920 children.
- Identified dominant risk characteristics through statistical analysis.
Main Results:
- 12.3% of children developed eczema before age five.
- Key predictors included maternal history of eczema, asthma, or hay fever.
- Higher parental education and maternal origin from West Indies/Africa were significant risk factors.
- Maternal contraceptive use prior to pregnancy also increased risk.
Conclusions:
- Childhood eczema is associated with several identifiable early risk factors.
- Maternal allergy history and socioeconomic factors play a role.
- Breastfeeding did not show a protective effect, even in mothers with allergy history.
Abstract:
Amongst a nationally representative sample of singletons born in one week of April 1970 for whom information was available, 12.3% were reported by their mothers as having developed eczema at some time before their fifth birthday. Data from both the birth and the five-year follow-up surveys have been analysed to identify the independent early predictors of this (reported) condition in 11,920 children. Using an initial set of possible predictors suggested by previous analyses of these data, the dominant risk characteristics have been identified as: a positive maternal history of eczema; a positive maternal history of asthma or hay fever; higher parental educational qualifications and the mother originating from the West Indies or Africa. There were also increased risks for children of mothers born in England (relative to the rest of the United Kingdom) and for children of mothers who used contraceptives in the 18 months prior to the index pregnancy. There was no protective effect of breast-feeding even among children whose mothers had a history of allergy.
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