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Updated: Oct 5, 2025

Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions
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Emerging SARS-CoV-2 Genotypes Show Different Replication Patterns in Human Pulmonary and Intestinal Epithelial Cells

Gabriel Augusto Pires de Souza1,2, Marion Le Bideau1,2, Celine Boschi1,2

  • 1Unité de Recherche Microbe Phylogeny and Evoluition (MEPHI), Institut de Recherche pour le Développement (IRD), Assistance Publique-Hôpitaux de Marseille (AP-HM), Aix-Marseille Université, 27 Boulevard Jean Moulin, 13005 Marseille, France.

Viruses
|January 22, 2022
PubMed
Summary

This study examined Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variant replication across different human cell lines. Findings reveal significant variations in replication, impacting viral spread and vaccine effectiveness.

Keywords:
COVID-19Caco-2 cellsCalu-3 cellsSARS-CoV-2Vero E6 cellsgenotypeisolatevariantsviral culture

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