Total Flight Hours and Other Factors Associated with Hyperuricemia in Civilian Pilots

BACKGROUND: In the aviation world, hyperuricemia can endanger flight safety through the risk of incapacitation, either associated with gout disease or associated with an increased risk of cardiovascular disease. This study aims to determine the prevalence of hyperuricemia in civil pilots in Indonesia and the identification of risk factors for hyperuricemia in civil pilots in Indonesia.METHODS: The study used a cross-sectional method from the medical records of civil pilots at the Aviation Medical Center, Jakarta, who were examined on 1 November 2019 through 30 April 2020. Data collected from medical records included: laboratory data of uric acid, age, total flight hours, Body Mass Index (BMI), and alcohol consumption. Hyperuricemia is a plasma urate concentration > 420 µmol · L^-1(7 mg · dl^-1).RESULTS: The research sample amounted to 5202 pilots; 18.4% had hyperuricemia. Pilots who have total flight hours ≥5000 have a reduced risk of hyperuricemia by 24% compared to pilots with total flight hours <5000. Obese and overweight pilots had a 2.98 times and 1.36 times, respectively, greater risk of hyperuricemia than pilots who had a normal BMI. Based on BMI criteria classification of WHO Asia Pacific, obese is ≥25 and overweight is 23-24.9. Furthermore, compared to pilots who did not consume alcohol, pilots who consumed alcohol had a 14.68 times greater risk of developing hyperuricemia.CONCLUSION: The prevalence of hyperuricemia in civil pilots in Indonesia is 18.4%. Obesity, overweight, and alcohol consumption increase the risk of hyperuricemia in civil pilots in Indonesia.Tisera SC, Agustina A, Soemarko DS.