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Related Concept Videos

Teratogenicity01:07

Teratogenicity

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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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The Thyroid Gland01:23

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
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Functions of Thyroid Hormones01:18

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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
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Spontaneous Murine Model of Anaplastic Thyroid Cancer
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Thyroid teratoma in a newborn.

Joseph Roscamp1, Sabapathy Balasubramanian2, Sanjeev L Gupta3

  • 1Academic Unit of Medical Education, The University of Sheffield, Sheffield, UK ja.roscamp@gmail.com.

BMJ Case Reports
|January 22, 2022
PubMed
Summary
This summary is machine-generated.

A rare congenital neck mass, a thyroid teratoma, caused respiratory distress in a newborn. Surgical removal led to full recovery, highlighting the importance of timely intervention for this serious diagnosis.

Keywords:
otolaryngology / ENTpaediatric intensive carepaediatric surgery

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Area of Science:

  • Pediatric Surgery
  • Neonatal Care
  • Otolaryngology

Background:

  • Congenital neck masses can present with severe respiratory distress in neonates.
  • Thyroid teratomas are rare tumors that can compromise the neonatal airway.

Observation:

  • A newborn presented with acute respiratory distress due to a neck mass.
  • Endoscopic airway assessment revealed a lesion in the right thyroid lobe.

Findings:

  • Open excision of the thyroid teratoma successfully resolved airway compromise.
  • Histological examination confirmed complete pathological clearance of the tumor.

Implications:

  • Prompt surgical management of neonatal thyroid teratomas is crucial for preventing morbidity and mortality.
  • Successful surgical outcomes are achievable with specialized neonatal intensive care and pediatric surgical expertise.