Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Leptospirosis from the clinical viewpoint.

K Ziegler1

  • 1W. Pieck University Rostock, GDR, Clinic of Internal Medicine.

Bulletin of the Institute of Maritime and Tropical Medicine in Gdynia
|January 1, 1987
PubMed
Summary

Accurate leptospirosis diagnosis is challenging due to sporadic cases, impacting early treatment. Serotype icterohaemorrhagiae is common, but direct detection is rare, with a moderately severe disease course and one fatality observed.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Short Note on the Density of States in 3D Weyl Semimetals.

Physical review letters·2018
Same author

Myeloid protein tyrosine phosphatase 1B (PTP1B) deficiency protects against atherosclerotic plaque formation in the ApoE<sup>-/-</sup> mouse model of atherosclerosis with alterations in IL10/AMPKα pathway.

Molecular metabolism·2017
Same author

EIectrical impedance and transepidermal water loss of healthy human skin under different conditions.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·2016
Same author

Superior functional outcome after femoral derotation osteotomy according to gait analysis in cerebral palsy.

Gait & posture·2014
Same author

Mobile stroke unit for diagnosis-based triage of persons with suspected stroke.

Neurology·2012
Same author

Nonlinear electromagnetic response of graphene: frequency multiplication and the self-consistent-field effects.

Journal of physics. Condensed matter : an Institute of Physics journal·2011

Area of Science:

  • Infectious Diseases
  • Epidemiology
  • Microbiology

Background:

  • Leptospirosis is an infectious disease with diverse clinical presentations.
  • Accurate and timely diagnosis of leptospirosis can be difficult, especially in sporadic outbreaks.
  • Understanding the prevalent serotypes and detection methods is crucial for disease management.

Purpose of the Study:

  • To present epidemiological, clinical, and microbiological data of leptospirosis patients.
  • To evaluate the accuracy of initial diagnosis in sporadic leptospirosis cases.
  • To identify common serotypes and assess detection methods for leptospirosis.

Main Methods:

  • Retrospective analysis of 27 patients diagnosed with leptospirosis.
  • Review of epidemiological, clinical, and microbiological data.
  • Agglutination tests for serotype identification.
  • Blood cultures for direct leptospire detection.

Main Results:

  • Correct diagnosis on admission was achieved in only 18% of patients.
  • Serotype icterohaemorrhagiae was the most frequent cause of infection.
  • Leptospires were detected directly in blood cultures in only one case.
  • The disease course was generally moderately severe, with one reported fatality.

Conclusions:

  • Sporadic occurrence of leptospirosis leads to diagnostic challenges.
  • Agglutination tests are valuable for serotype identification.
  • Direct detection of leptospires in blood is infrequent.
  • Leptospirosis can present as a moderately severe illness requiring careful clinical management.

Related Experiment Videos