18F-FDG PET/CT in Clear Cell Sarcoma With Multiple Bone Metastases

Area of Science:

• Oncology
• Radiology
• Pathology

Background:

• Clear cell sarcoma is a rare soft tissue sarcoma with a propensity for bone metastasis.
• Early diagnosis and staging are crucial for effective management of sarcomas.

Observation:

• A 26-year-old male presented with persistent facial pain, initially suspected as jaw osteomyelitis.
• Chest CT revealed extensive bone destructions, prompting further investigation for metastatic disease.

Findings:

• 18F-FDG PET/CT identified multiple skeletal and left arm lesions, indicating widespread metastases.
• Pathological and molecular analyses confirmed the diagnosis of clear cell sarcoma.

Implications:

• This case underscores the diagnostic challenges posed by rare tumors like clear cell sarcoma.
• Comprehensive imaging and pathological evaluation are vital for accurate staging and treatment planning in suspected metastatic bone disease.