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Approach to probiotics in pediatrics: the role of Lactobacillus rhamnosus GG

Christian Boggio Marzet1, Fernando Burgos2, Mónica Del Compare3

  • 1Grupo de Trabajo en Gastroenterología y Nutrición Pediátrica, Hospital General de Agudos Dr. Ignacio Pirovano, Ciudad Autónoma de Buenos Aires, Argentina.

Archivos Argentinos De Pediatria
|January 24, 2022
PubMed

Insights

Probiotics, particularly Lactobacillus rhamnosus GG, show promise in managing pediatric conditions like diarrhea and colic. Early use may also help prevent allergies and improve tolerance in infants.

Area of Science:

  • Pediatric medicine
  • Microbiology
  • Immunology

Background:

  • Noncommunicable diseases are rising, linked to factors like preterm birth, C-sections, antibiotic use, and limited breastfeeding.
  • Probiotics are increasingly explored for their potential health benefits in infants and children.

Purpose of the Study:

  • To conduct a descriptive review of probiotic applications in pediatrics.
  • To specifically focus on the efficacy and use of Lactobacillus rhamnosus GG.

Main Methods:

  • Descriptive review of existing literature on probiotic use in pediatrics.
  • Focused analysis on studies involving Lactobacillus rhamnosus GG and other relevant probiotics.

Main Results:

  • Probiotics, including Lactobacillus rhamnosus GG and Saccharomyces boulardii, are effective for acute and antibiotic-associated diarrhea.
  • Lactobacillus reuteri DSM 17938 and Lactobacillus rhamnosus GG aid in managing infant colic.
  • Lactobacillus rhamnosus GG in infant formula may enhance tolerance in cow's milk protein allergy.
  • Prenatal administration of Lactobacillus rhamnosus GG can reduce the incidence of atopic dermatitis in infants.

Conclusions:

  • Lactobacillus rhamnosus GG demonstrates significant potential across various pediatric applications.
  • Probiotics can be considered as valuable adjuvants in contemporary pediatric clinical practice.

Keywords:
Lactobacillus rhamnosus GGinfant formulasmicrobiotaprobiotics

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