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Potential metal-related strategies for prevention and treatment of COVID-19

Ya-Qiong Ni1, Hui-Hui Zeng1, Xian-Wen Song1

  • 1Hunan Provincial Key Laboratory of Micro and Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083 China.

Rare Metals
|January 24, 2022
PubMed

Insights

Metal-based drugs show promise for preventing and treating coronavirus disease 2019 (COVID-19). This review highlights metallohydrogels as effective antiviral agents against SARS-CoV-2, offering new therapeutic strategies.

Area of Science:

  • Pharmacology
  • Infectious Diseases
  • Materials Science

Background:

  • Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, presents significant global health and economic challenges.
  • Metal elements play crucial roles in immune responses, and metal-based compounds have a history of use as antiviral drugs and enzyme inhibitors.
  • Metal-based drugs offer unique pharmacological advantages due to their diverse chemical structures and broad bioactivities.

Purpose of the Study:

  • To review recent advancements in COVID-19 prevention and treatment strategies.
  • To explore the application of metal pharmacology in combating SARS-CoV-2.
  • To highlight the potential of metal-based drugs, particularly metallohydrogels, for COVID-19 therapy.

Main Methods:

  • Literature review of metal pharmacology applications in antiviral research.
  • Analysis of current and potential uses of metal-based drugs against COVID-19.
  • Focus on metallohydrogels and their antiviral properties.

Main Results:

  • Metal-based drugs are versatile and possess significant potential for managing viral infections like COVID-19.
  • Metallohydrogels demonstrate superior antiviral activities against SARS-CoV-2.
  • This review consolidates knowledge on metal-based therapeutic approaches for COVID-19.

Conclusions:

  • Metal pharmacology offers promising avenues for developing novel antiviral therapies against COVID-19.
  • Metallohydrogels represent a key area of development for effective COVID-19 treatment.
  • Further research into metal-based drugs is warranted for pandemic preparedness and response.
Keywords:
COVID-19Metal nutrient elementsMetal-related drugsMetallohydrogelSARS-CoV-2

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