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Updated: Oct 5, 2025

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Published on: September 5, 2016
Disseminated Intravascular Coagulation Due to Drinking Tonic Water
Sasmith R Menakuru1, Adelina Priscu1, Ahmed Salih1
1Internal Medicine, Indiana University Health Ball Memorial Hospital, Muncie, USA.
Abstract:
Quinine has been used worldwide to treat malaria; however, it is now used as an agent for night-time muscle cramping. The compound, derived from Cinchona tree bark, is found in antimalaria medication, supplements for leg cramping, and beverages such as tonic water and bitter lemon. Quinine, however, is not without its side effect profile which includes a wide range of ailments ranging from nausea to disseminated intravascular coagulation. The authors present a case of a 35-year-old man diagnosed with disseminated intravascular coagulation due to an excessive intake of tonic water because his friend told him that it would help alleviate nighttime leg cramping. We strive to inform physicians about the side effect profile of quinine and stress that a pertinent history must be elicited in patients with unknown causes of disseminated intravascular coagulation.
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