Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Abnormal Proliferation02:23

Abnormal Proliferation

4.7K
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
4.7K
Skin Cancer01:30

Skin Cancer

4.8K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.8K
Proliferative Phase01:20

Proliferative Phase

882
The proliferative phase typically occurs after menstruation and lasts between 6 to 13 days in a standard 28-day cycle. This phase involves the reconstruction of the endometrium, guided by estrogen produced by the developing ovarian follicle.
Notably, the stratum basale, the basal layer of the endometrium, including the basal parts of the uterine glands, remains unaffected by menstruation. Stem cells in this layer undergo mitosis, regenerating the stratum functionalis and thickening the...
882
Tumor Progression02:07

Tumor Progression

6.6K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

NLRP3 Inflammasome and IL-1-Mediated Inflammation in Human Carotid Atherosclerosis: A Systematic Review of Endarterectomy-Based Evidence.

Medical sciences (Basel, Switzerland)·2026
Same author

Novel Therapies, Residual Risk, Familial Hypercholesterolemia, and Digital Tools: Multispecialty Insights from a Dyslipidemia Management Survey.

Journal of clinical medicine·2026
Same author

Extranodal NK/T-Cell Lymphoma in the Nasal Region Illustrating the Differential Diagnosis of Lesions of the Face.

Clinical case reports·2026
Same author

RISE-ing to new heights: Porto Biomedical Journal adopts a new identity.

Porto biomedical journal·2026
Same author

Comparison of the Canal Transportation and Centering Ability of TruNatomy, WaveOne Gold and Protaper Ultimate: An Ex Vivo Study in Human Maxillary Molars.

European endodontic journal·2026
Same author

The microevolutionary trajectory of endemic multidrug-resistant tuberculosis strains in Portugal toward increased drug resistance levels and its clinical significance.

Frontiers in microbiology·2026

Related Experiment Video

Updated: Oct 5, 2025

Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation
09:43

Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation

Published on: January 14, 2014

8.2K

Pilomatrixoma Recurring as Giant Form.

Ana Teresa Tavares1, Manuel Neiva-Sousa2, Carina Semedo3

  • 1Stomathology Department, Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Lisbon, PRT.

Cureus
|January 24, 2022
PubMed
Summary

Pilomatrixoma, a benign skin tumor, can recur, especially in giant forms. Complete surgical excision is crucial for preventing recurrence and ensuring successful patient outcomes.

Keywords:
diferential diagnosisgiant pilomatrixomahead and neck surgeryhead and neck tumorspilomatrixomarecurrent pilomatrixomaskin adnexal tumor

More Related Videos

Translational Orthotopic Models of Glioblastoma Multiforme
07:37

Translational Orthotopic Models of Glioblastoma Multiforme

Published on: February 17, 2023

3.1K
Fully Human Tumor-based Matrix in Three-dimensional Spheroid Invasion Assay
08:15

Fully Human Tumor-based Matrix in Three-dimensional Spheroid Invasion Assay

Published on: May 7, 2019

15.9K

Related Experiment Videos

Last Updated: Oct 5, 2025

Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation
09:43

Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation

Published on: January 14, 2014

8.2K
Translational Orthotopic Models of Glioblastoma Multiforme
07:37

Translational Orthotopic Models of Glioblastoma Multiforme

Published on: February 17, 2023

3.1K
Fully Human Tumor-based Matrix in Three-dimensional Spheroid Invasion Assay
08:15

Fully Human Tumor-based Matrix in Three-dimensional Spheroid Invasion Assay

Published on: May 7, 2019

15.9K

Area of Science:

  • Dermatology
  • Surgical Oncology
  • Pathology

Background:

  • Pilomatrixoma is a benign skin neoplasm originating from the hair matrix, commonly affecting children and young adults.
  • Clinical presentation typically involves an asymptomatic, firm, solitary subcutaneous mass, often on the head and neck.
  • Preauricular location can lead to misdiagnosis as parotid tumors or other skin cysts.

Observation:

  • A case of a recurrent, giant pilomatrixoma in a male patient is presented.
  • The lesion's location and recurrent nature posed diagnostic and management challenges.
  • The patient presented with a large, previously treated pilomatrixoma.

Findings:

  • Complete surgical excision of the giant recurrent pilomatrixoma was successfully performed.
  • Post-operative follow-up revealed no signs of tumor recurrence.
  • The patient experienced no functional impairment following the surgical intervention.

Implications:

  • This case highlights the importance of thorough surgical technique in pilomatrixoma management.
  • Complete excision is essential to prevent recurrence, even in large or giant forms.
  • Accurate diagnosis and complete removal ensure favorable long-term outcomes for pilomatrixoma patients.