Fibromuscular Dysplasia: A Rare Case with Multiple Vascular Beds Involvement
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Updated: Oct 5, 2025

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1Department of Neurosurgery, Sarawak General Hospital, Sarawak, Malaysia.
Abstract:
Fibromuscular dysplasia (FMD) is an idiopathic, non-inflammatory, and non-atherosclerotic vascular disease of small- to medium-sized arteries. It can be occurred in almost all arteries and most commonly involving cervicocranial and renal arteries. FMD is commonly present as renovascular hypertension and affecting most young ladies. However, this case demonstrates a casuistically rare form of multiple arterial beds involvement at different sites, i.e. vertebral, coronary, hepatic, and lumbar arteries, with the conjunction of both bilateral renal and cervicocranial arteries.
Insights
Fibromuscular dysplasia (FMD) is a rare vascular condition affecting arteries. This case highlights a unique instance of FMD impacting multiple, diverse arterial locations simultaneously.
Area of Science:
- Vascular Medicine
- Radiology
- Genetics
Background:
- Fibromuscular dysplasia (FMD) is an idiopathic, non-inflammatory vascular disease affecting small to medium arteries.
- It commonly affects cervicocranial and renal arteries, often presenting as renovascular hypertension in young women.
Observation:
- This case presents a rare manifestation of FMD involving multiple arterial beds.
- The affected arteries included vertebral, coronary, hepatic, and lumbar arteries.
- This occurred concurrently with bilateral renal and cervicocranial artery involvement.
Findings:
- Demonstrates an exceptionally rare, multi-site arterial involvement pattern in FMD.
- Challenges the typical presentation of FMD by affecting diverse vascular territories.
- Highlights the potential for widespread arterial disease in FMD.
Implications:
- Suggests a need for broader vascular screening in FMD patients.
- May inform future research into FMD pathogenesis and genetic predispositions.
- Emphasizes the importance of considering FMD in unexplained multi-arterial pathologies.
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