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Updated: Oct 5, 2025

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance
Published on: December 28, 2017
Genome sequence data of the antagonistic soil-borne yeast Cyberlindnera sargentensis (SHA 17.2)
Maria Paula Rueda-Mejia1, Lukas Nägeli1, Stefanie Lutz2
1Agroscope, Research Division Plant Protection, Müller-Thurgau-Strasse 29, Wädenswil 8820, Switzerland.
Abstract:
Cyberlindnera sargentensis strain SHA 17.2, isolated from a Swiss soil sample, exhibited strong antagonistic activity against several plant pathogenic fungi in vitro and was highly competitive against other yeasts in soil. As a basis for identifying the mechanisms underlying its strong antagonistic activity, we have sequenced the genome of C. sargentensis (SHA 17.2) by long- and short read sequencing, de novo assembled them into seven contigs/chromosomes and a mitogenome (total genome size 11.4 Mbp), and annotated 5455 genes. This high-quality genome is the reference for transcriptome and proteome analyses aiming at elucidating the mode of action of C. sargentensis against fungal plant pathogens. It will thus serve as a resource for identifying potential biocontrol genes and performing comparative genomics analyses of yeast genomes.
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