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Mechanical tricuspid valve thrombosis: A midterm follow-up study
Maryam Shojaeifard1, Negar Omidi2, Sajad Erami3
1Departement of Echocardiography, Echocardiography Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
Mechanical tricuspid valve thrombosis is common and requires individualized management. Recurrent thrombosis is a major complication, highlighting the need for close patient follow-up.
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Biomedical Engineering
Background:
- Prosthetic tricuspid valve (TV) thrombosis occurs most frequently among heart valves.
- Untreated TV thrombosis leads to significant morbidity and mortality.
- This study focuses on the management and outcomes of mechanical TV thrombosis.
Purpose of the Study:
- To report the management strategies for patients with mechanical tricuspid valve thrombosis.
- To evaluate the clinical outcomes associated with different treatment approaches.
- To identify complications and long-term results in this patient cohort.
Main Methods:
- A retrospective analysis of 42 patients with mechanical TV thrombosis from 2006 to 2017.
- Assessment of baseline characteristics and adverse events during follow-up.
- Evaluation of treatment modalities including thrombolytic therapy, anticoagulant intensification, and surgery.
Main Results:
- 67 episodes of mechanical TV thrombosis were observed in 42 patients.
- Thrombolytic therapy was the primary approach in 61.1% of episodes.
- Recurrent thrombosis rates were 84% at 1 year, decreasing to 21% at 10 years.
- Survival and freedom from chronic valve dysfunction rates were high at 1 year (93% and 82%, respectively), declining over time.
Conclusions:
- Recurrent thrombosis is a significant complication of mechanical TV prostheses.
- Individualized therapeutic approaches are crucial for managing mechanical TV thrombosis.
- Close monitoring and follow-up are essential for patients with mechanical TV thrombosis.
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