Related Experiment Video
Updated: Oct 5, 2025

Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
Can PATH Study susceptibility measures predict e-cigarette and cigarette use among American youth 1 year later?
Ruoyan Sun1, David Mendez2, Kenneth E Warner2
1Department of Health Policy and Organization, University of Alabama at Birmingham School of Public Health, Birmingham, AL, USA.
Aims:
To investigate whether e-cigarette and cigarette susceptibility predict e-cigarette and cigarette use among American youth 1 year later.
Design And Setting:
Longitudinal data from the Population Assessment of Tobacco and Health (PATH) Study-a four-stage, stratified probability cohort study of youth (12-17 years old) sampled from the United States civilian, non-institutionalized population. Multivariable logistic regression was used to estimate the association between initial product-specific susceptibility and subsequent cigarette smoking and e-cigarette use while controlling for sociodemographic characteristics, exposure to nicotine users, and behavioral risk factors.
Participants:
The sample included 8841 adolescent never nicotine users at initial survey who participated in both wave 4 (2016-2017) and wave 4.5 (2017-2018) of PATH.
Measurements:
We measured cigarette and e-cigarette susceptibility (defined as a lack of a firm commitment to not use cigarettes or e-cigarettes) among never nicotine users at baseline (wave 4) as well as cigarette and e-cigarette use at 12-month follow-up (wave 4.5).
Findings:
Youth e-cigarette susceptibility was statistically significantly (P < 0.05) associated with e-cigarette use 1 year later, for both past 12-month (adjusted odds ratio [aOR], 2.99; 95% CI, 2.29-3.90) and past 30-day e-cigarette use (aOR, 2.73; 95% CI, 1.78-4.16), but not with cigarette smoking (aOR, 1.05; 95% CI, 0.64-1.73 for past 12-month smoking and aOR, 0.65; 95% CI, 0.29-1.45 for past 30-day smoking. Smoking susceptibility predicted subsequent smoking in the past 12 months (aOR, 1.82; 95% CI, 1.09-3.03) and past 30 days (aOR, 3.32; 95% CI (1.33-8.29), but not e-cigarette use in the past 12 months (aOR, 0.96; 95% CI, 0.77-1.19) or past 30 days (aOR, 1.11; 95% CI, 0.82-1.51).
Conclusion:
E-cigarette and cigarette susceptibility measures appear to predict product-specific use among youth 1 year later.
More Related Videos
08:39Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
Published on: August 25, 2018
09:50Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke
Published on: February 12, 2015
Related Concept Videos
Statistical Methods for Analyzing Epidemiological Data
Stimulants
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Observational Studies
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
Bias in Epidemiological Studies
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Longitudinal Research