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Published on: March 27, 2018
Effect of Different Blood Groups on Long-Term Outcomes of Surgical Revascularisation
Negin Yavari1, Farzad Masoudkabir2, Mina Ghorbanpour Landy1
1Department of Cardiovascular Research, Tehran Heart Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Insights
ABO blood groups do not impact long-term outcomes after coronary artery bypass graft (CABG) surgery. This study found no significant association between blood type and major adverse cardiocerebrovascular events (MACCE) in CABG patients.
Area of Science:
- Cardiovascular Surgery
- Transfusion Medicine
- Clinical Outcomes Research
Background:
- ABO blood groups are linked to cardiovascular disease risk.
- The influence of ABO blood groups on coronary artery bypass graft (CABG) surgery outcomes remains unclear.
- This study investigates the predictive value of ABO blood groups for long-term adverse events in CABG patients.
Purpose of the Study:
- To determine if ABO blood groups predict long-term major adverse cardiocerebrovascular events (MACCE) in patients undergoing CABG.
- To clarify the relationship between ABO blood groups and clinical outcomes following CABG surgery.
Main Methods:
- Retrospective cohort study of 17,713 patients undergoing isolated CABG.
- Patients categorized into four ABO blood group subgroups.
- Cox regression survival analysis used to assess the association between ABO blood groups and MACCE.
Main Results:
- Multivariable analysis revealed no significant difference in 5-year mortality or 5-year MACCE among different ABO blood groups.
- The study included a large cohort with extensive follow-up data.
Conclusions:
- ABO blood groups are not associated with long-term MACCE in patients who underwent CABG.
- Blood type does not appear to be a significant prognostic factor for adverse outcomes after CABG surgery.
Background:
ABO blood groups are considered to be associated with cardiovascular disease. Nonetheless, the definite effect of ABO blood groups on the clinical outcome of coronary artery bypass graft surgery (CABG) is still undetermined. We evaluated whether ABO blood groups can predict long-term major adverse cardiocerebrovascular events (MACCE) in CABG patients.
Method:
In this retrospective cohort study, we retrieved the clinical files of eligible patients treated with isolated CABG in our hospital between March 2007 and March 2016. We divided the patients into four ABO subgroups. The primary study endpoints were the occurrence of all-cause mortality and MACCE during long-term follow-ups. We used Cox regression survival analysis to define the association of ABO blood groups with the occurrence of MACCE.
Results:
Of 17,892 patients who underwent isolated CABG, 17,713 (mean age, 61.19±9.47 years, 74.6% male) were successfully followed, and their data used in the final analysis. Our multivariable analysis demonstrated that patients with different blood groups had similar 5-year mortality and 5-year MACCE.
Conclusions:
Our findings suggest that in patients who underwent CABG, ABO blood groups were not associated with long-term MACCE.
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