Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Turbulence-resilient detection of the rotational Doppler effect with cylindrical vector beams.

Optics express·2023
Same author

DIW1 encoding a clade I PP2C phosphatase negatively regulates drought tolerance by de-phosphorylating TaSnRK1.1 in wheat.

Journal of integrative plant biology·2023
Same author

Effects of Breathing Exercises in Patients With Chronic Obstructive Pulmonary Disease: A Network Meta-analysis.

Archives of physical medicine and rehabilitation·2023
Same author

Disheveled3 enhanced EMT and cancer stem-like cells properties via Wnt/β-catenin/c-Myc/SOX2 pathway in colorectal cancer.

Journal of translational medicine·2023
Same author

Association of meibomian gland morphology with orifice plugging and lid margin thickening in meibomian gland dysfunction patients.

International ophthalmology·2023
Same author

Asymmetric Radical Bicyclization for Stereoselective Construction of Tricyclic Chromanones and Chromanes with Fused Cyclopropanes.

Journal of the American Chemical Society·2023

Related Experiment Video

Updated: Oct 5, 2025

Rapid Fabrication of Custom Microfluidic Devices for Research and Educational Applications
05:33

Rapid Fabrication of Custom Microfluidic Devices for Research and Educational Applications

Published on: November 20, 2019

8.9K

Time-efficient fabrication method for 3D-printed microfluidic devices.

Yan Jin1, Peng Xiong1, Tongyu Xu1,2

  • 1College of Information and Electrical Engineering, Shenyang Agricultural University, Shenyang, 110866, China.

Scientific Reports
|January 25, 2022
PubMed
Summary
This summary is machine-generated.

This study introduces a fast and affordable 3D-printing method for microfluidic devices using Dowsil 732. An optimization model ensures high accuracy in fabricating essential microfluidic components.

More Related Videos

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods
07:51

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods

Published on: December 23, 2013

7.5K
Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays
11:33

Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays

Published on: March 9, 2017

15.9K

Related Experiment Videos

Last Updated: Oct 5, 2025

Rapid Fabrication of Custom Microfluidic Devices for Research and Educational Applications
05:33

Rapid Fabrication of Custom Microfluidic Devices for Research and Educational Applications

Published on: November 20, 2019

8.9K
High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods
07:51

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods

Published on: December 23, 2013

7.5K
Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays
11:33

Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays

Published on: March 9, 2017

15.9K

Area of Science:

  • Materials Science
  • Microfluidics Engineering

Background:

  • 3D-printing offers a cost-effective alternative for microfluidic device fabrication.
  • Current 3D-printed microfluidic systems face challenges including post-processing, opacity, and time consumption, hindering practical use.

Purpose of the Study:

  • To develop a time-efficient and inexpensive fabrication method for 3D-printed microfluidic devices.
  • To evaluate Dowsil 732 as a material for 3D-printed microfluidic chips.
  • To propose an optimization model for direct ink writing to enhance fabrication accuracy and speed.

Main Methods:

  • Utilized Dowsil 732, a common industrial sealant, for 3D-printed microfluidic chip fabrication.
  • Assessed curing time and surface hydrophobicity of Dowsil 732, confirming its hydrophilic nature.
  • Developed and validated an optimization model for the direct ink writing process, correlating printing speed, pressure, and channel accuracy.

Main Results:

  • The developed method using Dowsil 732 proved to be time-efficient and inexpensive.
  • The optimization model accurately predicted the relationship between printing parameters and channel wall accuracy, achieving over 95% accuracy.
  • Demonstrated the fabrication of functional microfluidic devices, including a micromixer, concentration gradient generator, and droplet generator.

Conclusions:

  • The proposed fabrication method and optimization model significantly improve the efficiency and accuracy of 3D-printed microfluidic devices.
  • Dowsil 732 is a viable material for creating functional microfluidic devices with a hydrophilic surface.
  • This advancement facilitates broader practical applications of 3D-printed microfluidics.