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Updated: Oct 5, 2025

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
Impact of COVID-19 lockdown on progressive multiple sclerosis patients
Marco Vercellino1, Chiara Bosa2, Anastasia Alteno2
1Multiple Sclerosis Center, Neurologia I U, Department of Neuroscience and Mental Health, AOU Città della Salute e della Scienza di Torino, Via Cherasco 15, 10126, Torino, Italy. marco.vercellino@unito.it.
Introduction:
The COVID-19 pandemic caused major changes in the lifestyle and in the access to health services worldwide. Progressive multiple sclerosis (pMS) patients are a vulnerable population at high risk of disability worsening.
Objective And Methods:
The objective of this study was to assess the health outcomes of COVID-19 lockdown in a cohort of 225 pMS patients.
Results:
Worsening of neurological disability (19.7%) and fatigue (32.4%), depression (30.4%), and weight increase (28.3%) were observed in pMS patients during lockdown, along with discontinuation of regular physical exercise (47.1%) and of physical therapy (59.3%).
Conclusion:
These results highlight the adverse impact, on pMS patients, of the public health measures implemented for the containment of the pandemic.
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