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Larger Physique as a Risk Factor for Infantile Appendicitis: A Retrospective Study
Katsuhiro Nishimura1, Keita Terui1, Naoko Mise2
1Department of Pediatric Surgery, Graduate School of Medicine, Chiba University, Chiba 260-8677, Japan.
Insights
Larger infants with acute appendicitis have a bigger physique but normal proportions. This finding suggests that larger infants presenting with abdominal pain should be screened for appendicitis.
Area of Science:
- Pediatric Surgery
- Clinical Pediatrics
- Medical Research
Background:
- Acute appendicitis clinical features and risk factors in infants remain unclear.
- Understanding these factors is crucial for timely diagnosis and treatment in young children.
Purpose of the Study:
- To evaluate the association between anthropometrics and the occurrence of infantile appendicitis.
- To compare anthropometric Z-scores between infants and school-age children with appendicitis.
Main Methods:
- Retrospective study of Asian ethnicity infants (<6 years) and school-age children (6-10 years) hospitalized for appendicitis (2004-2018).
- Comparison of Z-scores for height, body weight, and body mass index (BMI) between groups and between perforated/non-perforated appendicitis in infants.
- Data analyzed from 73 infants and 362 school-age children.
Main Results:
- Infants showed significantly greater Z-scores for height (0.37 vs -0.03, p=0.003) and body weight (0.12 vs -0.36, p=0.023) compared to school-age children.
- No significant difference in BMI Z-scores between infants and school-age children.
- No difference in anthropometric Z-scores between perforated and non-perforated appendicitis groups in infants.
Conclusions:
- Infants with acute appendicitis tend to have a larger physique but normal body proportions, a trend not seen in school-age children.
- Larger infants presenting with abdominal pain warrant screening for appendicitis.
- Further research may elucidate specific risk factors and improve diagnostic accuracy in this population.
Abstract:
The clinical features and risk factors of acute appendicitis in infants are unclear. Our aim was to evaluate the association between anthropometrics and the occurrence of infantile appendicitis. This was a retrospective study of infants (<6 years of age) and school-age children (6-10 years of age) of Asian ethnicity who required hospitalization for appendicitis at our two participating institutions between 2004 and 2018. The Z-score for height, body weight, and body mass index (BMI) was compared between the two groups, as well as between patients presenting with perforated and non-perforated appendicitis. The analysis included data from 73 infants and 362 school-age children. Z-scores were greater in infants than in school-age children for height (0.37 versus -0.03, p = 0.003) and body weight (0.12 versus -0.36, p = 0.023), with no between-group difference for the Z-score of BMI. There was no difference in Z-scores for height, weight, and BMI between the perforated and non-perforated appendicitis infant groups. Infants presenting with acute appendicitis were characterized by a larger physique but with normal proportion. This trend was not observed in school-age children. Therefore, larger infants presenting with abdominal pain should be screened for appendicitis.
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