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Cells respond to space microgravity through cytoskeleton reorganization.

Xin-Tong Wu1, Xiao Yang1, Ran Tian1

  • 1Key Laboratory for Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, China.

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
|January 25, 2022
PubMed
Summary

Space microgravity causes cellular changes by disrupting the cytoskeleton (CSK). This review proposes a "cellular mechanical equilibrium" model explaining how gravity changes impact cell structure, function, and signaling pathways.

Keywords:
bonecellcytoskeletonmicrogravitymusclespace flight

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