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Updated: Aug 10, 2026

A Protocol for Computer-Based Protein Structure and Function Prediction
16:41

A Protocol for Computer-Based Protein Structure and Function Prediction

Published on: November 3, 2011

Evaluation and improvements in the automatic alignment of protein sequences

G J Barton1, M J Sternberg

  • 1Department of Crystallography, Birkbeck College, London, UK.

Protein Engineering
|February 1, 1987
PubMed
Summary

Assessing protein sequence alignment accuracy reveals that incorporating secondary structure information significantly improves results. This method can achieve over 75% accuracy in secondary structural regions for homologous protein sequences.

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