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[PRIMARY GASTRIC PLASMACYTOMA IN A BREAST CANCER MALE PATIENT]
Noam Asna1, Mark Shlapobersky2, Moshe Schaffer3
1Institute of Oncology, Ziv Medical Center, Zefat, Israel.
Harefuah
|January 25, 2022
Summary
This case report details a rare gastric plasmacytoma diagnosed in a male patient with a history of breast cancer. Radical gastrectomy provided both diagnosis and treatment for this unusual hematologic malignancy.
Area of Science:
- Hematologic Malignancies
- Gastrointestinal Oncology
Background:
- Extra-medullary plasmacytoma, a rare plasma cell tumor, can manifest as a primary gastric malignancy.
- Gastric plasmacytomas present with non-specific symptoms and lack standardized treatment protocols.
- The prognosis is often linked to the potential development of multiple myeloma.
Observation:
- A male patient with prior advanced breast cancer and hormonal therapy presented with melena.
- A large gastric lesion was identified, but biopsies yielded inconclusive results, complicating differential diagnosis between metastasis and a new primary tumor.
- Clinical deterioration necessitated surgical intervention for diagnosis.
Findings:
- Radical gastrectomy unexpectedly diagnosed a primary gastric plasmacytoma.
- This diagnosis was particularly rare given the patient's history of male breast cancer and maternal multiple myeloma.
- The surgical procedure served as the definitive treatment for the gastric plasmacytoma.
Implications:
- Highlights the importance of considering rare diagnoses in patients with complex medical histories.
- Emphasizes the diagnostic challenges posed by gastric lesions in cancer survivors.
- Demonstrates that surgical resection can be curative for primary gastric plasmacytoma.
