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Tertiary Healthcare System01:21

Tertiary Healthcare System

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Specialized care provided over an extended period is called tertiary care. Usually, a primary or secondary care physician will refer a patient to tertiary care. A patient's maximum physical and mental function is restored in tertiary care, which is caused due to the impact of a chronic illness or condition. Tertiary care aims to achieve the highest level of functioning possible while managing chronic illness. For example, a patient who falls and fractures their hip will need secondary care...
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Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

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In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
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Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

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Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
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Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
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Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

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Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
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COVID 19 In Children: An Experience From A Paediatric Tertiary Care Setting.

Saima Bibi1, Syed Yasir Hussain Gilani2, Zaheer Abbas1

  • 1Department of Paediatrics, Ayub Medical Teaching Institute, Abbottabad, Pakistan.

Journal of Ayub Medical College, Abbottabad : JAMC
|January 25, 2022
PubMed
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COVID-19 in children presents variably, with fever and cough common. Multisystem Inflammatory Syndrome in Children (MIS-C) is a key concern, requiring careful diagnosis in pediatric cases.

Keywords:
Inflammatory markersSARS-COV-2; Multisystem inflammatory syndrome

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Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Public Health

Background:

  • Limited data exists on COVID-19 in pediatric populations.
  • Understanding disease manifestations in children is crucial for effective management.
  • The SARS-CoV-2 pandemic necessitates research into its impact on all age groups.

Purpose of the Study:

  • To describe the clinical presentations of COVID-19 in children.
  • To analyze laboratory parameters, complications, and outcomes in pediatric SARS-CoV-2 cases.
  • To provide insights into the disease's behavior in the pediatric population.

Main Methods:

  • A descriptive case series was conducted on children with confirmed SARS-CoV-2 infection.
  • Data was collected from patients admitted to the pediatric unit.
  • Statistical analysis was performed using SPSS 26.0.

Main Results:

  • Seventeen pediatric patients (76.5% male) were included.
  • Fever and cough were the most common symptoms (88.2%).
  • Major complications included shock (76.5%), respiratory issues (94.11%), and MIS-C (52.9%).

Conclusions:

  • Paediatric COVID-19 exhibits diverse clinical presentations.
  • Multisystem Inflammatory Syndrome in Children (MIS-C) should be considered in children with organ dysfunction.
  • Early recognition and management are vital for improving outcomes in pediatric SARS-CoV-2 infections.