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COVID 19 In Children: An Experience From A Paediatric Tertiary Care Setting
Saima Bibi1, Syed Yasir Hussain Gilani2, Zaheer Abbas1
1Department of Paediatrics, Ayub Medical Teaching Institute, Abbottabad, Pakistan.
Insights
COVID-19 in children presents variably, with fever and cough common. Multisystem Inflammatory Syndrome in Children (MIS-C) is a key concern, requiring careful diagnosis in pediatric cases.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Limited data exists on COVID-19 in pediatric populations.
- Understanding disease manifestations in children is crucial for effective management.
- The SARS-CoV-2 pandemic necessitates research into its impact on all age groups.
Purpose of the Study:
- To describe the clinical presentations of COVID-19 in children.
- To analyze laboratory parameters, complications, and outcomes in pediatric SARS-CoV-2 cases.
- To provide insights into the disease's behavior in the pediatric population.
Main Methods:
- A descriptive case series was conducted on children with confirmed SARS-CoV-2 infection.
- Data was collected from patients admitted to the pediatric unit.
- Statistical analysis was performed using SPSS 26.0.
Main Results:
- Seventeen pediatric patients (76.5% male) were included.
- Fever and cough were the most common symptoms (88.2%).
- Major complications included shock (76.5%), respiratory issues (94.11%), and MIS-C (52.9%).
Conclusions:
- Paediatric COVID-19 exhibits diverse clinical presentations.
- Multisystem Inflammatory Syndrome in Children (MIS-C) should be considered in children with organ dysfunction.
- Early recognition and management are vital for improving outcomes in pediatric SARS-CoV-2 infections.
Background:
The pandemic of COVID 19 has affected a number of people around the globe. The data from paediatric population is scarce. The present study is aimed to present the paediatric perspective of the disease in terms of different clinical presentations, laboratory parameters, complications, and outcomes so as to develop an insight into disease manifestations in children.
Methods:
This descriptive case series was conducted in the department of Paediatrics after approval of institutional review board. All children admitted in paediatric unit with confirmed SARS-COV-2 infection either by PCR or antibody test were included in the study. Patients' characteristics were documented on a predesigned proforma and analysed using SPSS 26.0.
Results:
A total of 17 patients comprising 13 (76.5%) male and 4(23.5%) female were included in the study. The major clinical features were fever, cough and shortness of breath documented in 15 (88.2 %) patients. Major complications were shock in 13 (76.5%), respiratory complications in 16 (94.11%), CNS complications in 4 (23.5%), cardiac complications in 5 (29.4%), hepatic involvement in 3 (17.6%) Acute Kidney Injury in 4 (23.5%) patients and 9 (52.9 %) patients were labelled as having Multisystem Inflammatory Syndrome in Children (MIS-C). A total of 7 (41.2%) patients had coexistent comorbid diseases. A total of 13 (76.47%) patients were discharged, 2 (11.8%) patients expired and 2 (11.8%) left against medical advice.
Conclusion:
The clinical presentation of paediatric patients with SARS-COV-2 infection is highly variable. Multisystem inflammatory syndrome associated with SARS-COV-2 must be considered in the differential diagnosis of children presenting with multiorgan dysfunction.
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