Axis specification: Breaking symmetry with a myosin patch in the egg
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Updated: Oct 5, 2025

Analysis of Actomyosin Dynamics at Local Cellular and Tissue Scales Using Time-lapse Movies of Cultured Drosophila Egg Chambers
Published on: June 3, 2019
1Department of Cell and Systems Biology, University of Toronto, Toronto, ON M5S 3G5, Canada.
Abstract:
Drosophila anterior-posterior axis specification occurs in the oocyte, but the initial symmetry break has been unclear. A new study reveals that a posterior domain of cortical myosin is induced with unique post-translational modification and dynamics and that this domain recruits downstream posterior determinants.
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