Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prediction of Viscosity and Film Thickness for Laser Cutting Protective Fluid Based on Physics-Enhanced Machine Learning.

The journal of physical chemistry. B·2026
Same author

Sulfur Doping Induces Interfacial Water Regulation on Bi-Based Catalysts for Efficient Electrochemical CO<sub>2</sub> Reduction to Formate.

ChemSusChem·2026
Same author

Recycling and Reuse of a Sugar-Based Nonionic Surfactant Enabled by Redox-Switchable Precipitation-Dissolution.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Liquid metal capsules for autonomic thermal energy control.

RSC advances·2026
Same author

Regioselective Lipase Anchoring on Janus Nanoparticles Enables Directional Oil-Water Interfacial Assembly in Pickering Emulsions for Enhanced Biocatalysis.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Unravelling the mechanisms behind the stabilization of oil foams using soybean lecithin.

Journal of colloid and interface science·2026

Related Experiment Video

Updated: Oct 5, 2025

Aqueous Droplets Used as Enzymatic Microreactors and Their Electromagnetic Actuation
08:27

Aqueous Droplets Used as Enzymatic Microreactors and Their Electromagnetic Actuation

Published on: August 28, 2017

5.5K

Pickering emulsion droplet-based biomimetic microreactors for continuous flow cascade reactions.

Ming Zhang1, Rammile Ettelaie2, Lianlian Dong1

  • 1School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan, 030006, China.

Nature Communications
|January 26, 2022
PubMed
Summary

Continuous flow cascade catalysis is advanced using Pickering emulsions as cell-like microreactors. This biomimetic approach significantly boosts catalytic efficiency and enantioselectivity in multi-step reactions.

More Related Videos

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology
07:03

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology

Published on: December 1, 2023

1.1K
A Femtoliter Droplet Array for Massively Parallel Protein Synthesis from Single DNA Molecules
10:45

A Femtoliter Droplet Array for Massively Parallel Protein Synthesis from Single DNA Molecules

Published on: June 20, 2020

10.4K

Related Experiment Videos

Last Updated: Oct 5, 2025

Aqueous Droplets Used as Enzymatic Microreactors and Their Electromagnetic Actuation
08:27

Aqueous Droplets Used as Enzymatic Microreactors and Their Electromagnetic Actuation

Published on: August 28, 2017

5.5K
Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology
07:03

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology

Published on: December 1, 2023

1.1K
A Femtoliter Droplet Array for Massively Parallel Protein Synthesis from Single DNA Molecules
10:45

A Femtoliter Droplet Array for Massively Parallel Protein Synthesis from Single DNA Molecules

Published on: June 20, 2020

10.4K

Area of Science:

  • Chemical Engineering
  • Catalysis
  • Biomimetic Chemistry

Background:

  • Continuous flow cascade catalysis offers a revolutionary approach to stepwise synthesis.
  • Practical implementation remains challenging due to difficulties in managing multi-step reactions in flow.

Purpose of the Study:

  • To develop a practical method for one-pot cascade catalysis using continuous flow.
  • To enhance catalytic efficiency and enantioselectivity in complex chemical transformations.

Main Methods:

  • Combining Pickering emulsions with continuous flow technology.
  • Creating cell-like microreactors by co-localizing catalytic sub-compartments within emulsion droplets.
  • Packing microreactors in a column for continuous flow cascade catalysis.

Main Results:

  • Achieved 5–420 fold enhancement in catalysis efficiency.
  • Obtained up to 99% enantioselectivity in chemo-enzymatic cascade reactions.
  • Demonstrated sustained high performance over 80–240 hours of continuous operation.

Conclusions:

  • Pickering emulsion-based microreactors enable practical continuous flow cascade catalysis.
  • Compartmentalization and reactant enrichment within biomimetic microreactors are key to boosting efficiency and controlling kinetics.
  • This method offers a robust platform for efficient and selective synthesis of chiral molecules.