Related Experiment Video
Updated: Oct 5, 2025

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
Published on: March 3, 2023
COVID-19 lockdown, personal protective equipment, hyper-hygiene and allergy
G Liccardi1, M B Bilò2,3, M Milanese4
1Department of Experimental Medicine, Postgraduate School of Respiratory Medicine, University of Rome Tor Vergata, Rome, Italy.
The COVID-19 pandemic containment measures, including personal protective equipment (PPE) and sanitizers, impacted patients with allergic diseases. Further research is needed to understand risks associated with PPE and sanitizing agents, especially for healthcare workers.
Area of Science:
- Immunology
- Public Health
- Environmental Health
Background:
- The COVID-19 pandemic necessitated community-wide containment measures like lockdowns and personal protective equipment (PPE) use.
- These measures, while curbing viral spread, presented both beneficial and detrimental effects on individuals with pre-existing allergic diseases.
- The long-term implications of widespread PPE and disinfectant use on public health and allergies remain largely unexplored.
Purpose of the Study:
- To explore the multifaceted effects of COVID-19 containment strategies on allergic disease patients.
- To identify risk factors contributing to adverse outcomes, particularly among healthcare professionals frequently using PPE and sanitizers.
- To advocate for further research into the allergenic and toxic potentials of materials used in PPE and disinfectants.
Main Methods:
- Review of existing literature on COVID-19 containment measures and their impact on allergic conditions.
- Analysis of potential correlations between SARS-CoV-2 infection and allergic disease exacerbation or development.
- Identification of knowledge gaps concerning the health effects of prolonged exposure to PPE and sanitizing agents.
Main Results:
- Containment measures yielded mixed outcomes for patients with allergic diseases.
- Healthcare professionals using PPE and sanitizers extensively may face heightened risks of adverse effects.
- The widespread, long-term use of PPE and sanitizing agents necessitates a deeper understanding of their potential health impacts.
Conclusions:
- Further investigation is crucial to elucidate the relationship between SARS-CoV-2, allergy, and containment measures.
- Research should focus on the specific risks posed by PPE materials and sanitizing agents to identify and mitigate potential allergens and toxins.
- Proactive research is essential to ensure the safety of both healthcare workers and the general population as pandemic-related protective measures continue.
Related Concept Videos
Allergic Reactions
Standard Precaution
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Asthma-I: Introduction
Hypersensitivities
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
Allergic Drug Reactions

